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Targeting Different Biological Systems The body has redundant systems for maintaining weight

contraindicated in neonates

The mean percent change from baseline in bodyweight at week 72 was 12.8% with tirzepatide 10 mg, 14.7% with tirzepatide 15 mg, and 3.2% with placebo

Adults generally require around 1.5 micrograms per day and pregnant or breastfeeding women require up to 2.8 micrograms a day

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The most commonly reported adverse events in Phase 2 and Phase 3 trials were gastrointestinal in nature, including nausea, diarrhea, vomiting, and constipation